[PDB-UF at HARVARD] PDB - Unknown Function (2167 selected proteins from Structural Genomics) [PDB-UF at BIOINFO.PL]

Show of 2167 sorted by PDB Code   Length   3D-Hit Score   3D-Fun Z-score   Function   in ascending order
that (don't ) contain expression: (e.g.  1ns5A   or   2.1.1.   or   Methyltransferases)

No PDB
Code		 Protein
Length		 3D-Hit
Score		 3D-Hit
EC Number		 3D-Fun
Z-score		 3D-Fun
EC Number		 Report
Error		 Hypothetical Enzyme Function Predicted by both Programs
1. 
1u60A
 309 252.1 3. 5. 1. n 15.70 3. 5. 1. n [Er] Hydrolases • Acting on carbon-nitrogen bonds, other than peptide bonds • In linear amides
2. 
1m6yA
 289 289.0 2. 1. 1.? 14.47 2. 1. 1.? [Er] Transferases • Transferring one-carbon groups • Methyltransferases
3. 
1z84A
 311 237.6 2. 7. 7.? 14.14 2. 7. 7.? [Er] Transferases • Transferring phosphorus-containing groups • Nucleotidyltransferases
4. 
1lvwA
 295 295.0 2. 7. 7. n 14.04 2. 7. 7. n [Er] Transferases • Transferring phosphorus-containing groups • Nucleotidyltransferases
5. 
1zwjA
 301 234.3 2. 7. 7.? 13.93 2. 7. 7.? [Er] Transferases • Transferring phosphorus-containing groups • Nucleotidyltransferases
6. 
1lvwC
 292 291.0 2. 7. 7. n 13.83 2. 7. 7. n [Er] Transferases • Transferring phosphorus-containing groups • Nucleotidyltransferases
7. 
1vdwA
 248 235.1 3. 1. 3. n 13.71 3. 1. 3. n [Er] Hydrolases • Acting on ester bonds • Phosphoric monoester hydrolases
8. 
1zx5A
 296 224.6 5. 3. 1. n 13.63 5. 3. 1. n [Er] Isomerases • Intramolecular oxidoreductases • Interconverting aldoses and ketoses
9. 
1m6yB
 274 271.9 2. 1. 1.? 13.54 2. 1. 1.? [Er] Transferases • Transferring one-carbon groups • Methyltransferases
10. 
1t9kA
 332 299.0 5. 3. 1. n 13.51 5. 3. 1. n [Er] Isomerases • Intramolecular oxidoreductases • Interconverting aldoses and ketoses
11. 
1xi6A
 234 226.3 3. 1. 3. n 13.14 3. 1. 3. n [Er] Hydrolases • Acting on ester bonds • Phosphoric monoester hydrolases
12. 
1t2bA
 397 281.8 1. 14. 15. n 13.08 1. 14. 15. n [Er] Oxidoreductases • Acting on paired donors with incorporation of molecular oxygen • With a reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
13. 
1ue8A
 367 275.8 1. 14. 14.? 12.90 1. 14. 14.? [Er] Oxidoreductases • Acting on paired donors with incorporation of molecular oxygen • With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
14. 
1pt7A
 415 283.1 2. 8. 3.? 12.88 2.?.?.? [Er] Transferases
15. 
1kutB
 218 218.0 6. 3. 2. n 12.74 6. 3. 2. n [Er] Ligases • Forming carbon-nitrogen bonds • Acid-D-amino-acid ligases (peptide synthases)
16. 
1xdiA
 459 278.7 1. 8. 1. n 12.51 1. 8. 1. n [Er] Oxidoreductases • Acting on a sulfur group of donors • With NAD+ or NADP+ as acceptor
17. 
1inlA
 285 285.0 2. 5. 1. n 12.25 2. 5. 1. n [Er] Transferases • Transferring alkyl or aryl groups, other than methyl groups • Transferring alkyl or aryl groups, other than methyl groups
18. 
1inlB
 291 283.9 2. 5. 1. n 12.20 2. 5. 1. n [Er] Transferases • Transferring alkyl or aryl groups, other than methyl groups • Transferring alkyl or aryl groups, other than methyl groups
19. 
1inlD
 282 281.0 2. 5. 1. n 12.06 2. 5. 1. n [Er] Transferases • Transferring alkyl or aryl groups, other than methyl groups • Transferring alkyl or aryl groups, other than methyl groups
20. 
1wu8A
 250 215.0 2. 5. 1. n 11.99 2. 5. 1. n [Er] Transferases • Transferring alkyl or aryl groups, other than methyl groups • Transferring alkyl or aryl groups, other than methyl groups
21. 
1inlC
 293 278.8 2. 5. 1. n 11.83 2. 5. 1. n [Er] Transferases • Transferring alkyl or aryl groups, other than methyl groups • Transferring alkyl or aryl groups, other than methyl groups
22. 
1pvtA
 223 191.6 4. 1. 2. n 11.74 4.?. 2. n [Er] Lyases
23. 
2hi1A
 318 244.8 1. 1. 1. n 11.69 1. 1. 1. n [Er] Oxidoreductases • Acting on the CH-OH group of donors • With NAD+ or NADP+ as acceptor
24. 
1xq9A
 241 238.1 5. 4. 2. n 11.65 5. 4. 2. n [Er] Isomerases • Intramolecular transferases (mutases) • Phosphotransferases (phosphomutases)
25. 
1kutA
 209 196.8 6. 3. 2. n 11.39 6. 3. 2. n [Er] Ligases • Forming carbon-nitrogen bonds • Acid-D-amino-acid ligases (peptide synthases)
26. 
1nqkA
 345 299.0 1.?.?.? 11.32 1.?.?.? [Er] Oxidoreductases
27. 
1vjtA
 456 268.3 3. 2. 1. n 11.21 3. 2. 1. n [Er] Hydrolases • Glycosidases • Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds
28. 
2o1oB
 331 243.0 2. 5. 1.? 11.17 2. 5. 1.? [Er] Transferases • Transferring alkyl or aryl groups, other than methyl groups • Transferring alkyl or aryl groups, other than methyl groups
29. 
2hi1B
 314 234.5 1. 1. 1. n 11.15 1. 1. 1. n [Er] Oxidoreductases • Acting on the CH-OH group of donors • With NAD+ or NADP+ as acceptor
30. 
2o1oA
 335 239.4 2. 5. 1.? 11.11 2. 5. 1.? [Er] Transferases • Transferring alkyl or aryl groups, other than methyl groups • Transferring alkyl or aryl groups, other than methyl groups
31. 
1nnhA
 293 207.9 6. 1. 1.? 11.10 6. 3. 1. n [Er] Ligases
32. 
2azpA
 318 166.1 5. 1. 1. n 11.05 5. 1. 1. n [Er] Isomerases • Racemases and epimerases • Acting on amino acids and derivatives
33. 
1z90A
 460 233.7 2. 7. 7.? 10.86 2. 7. 7.? [Er] Transferases • Transferring phosphorus-containing groups • Nucleotidyltransferases
34. 
1kq3A
 364 280.0 1. 1. 1. n 10.83 1. 1. 1. n [Er] Oxidoreductases • Acting on the CH-OH group of donors • With NAD+ or NADP+ as acceptor
35. 
1sg9A
 274 260.8 2. 1. 1.? 10.76 2. 1. 1.? [Er] Transferases • Transferring one-carbon groups • Methyltransferases
36. 
1ri6A
 333 228.6 5. 5. 1. n 10.57 5. 5. 1. n [Er] Isomerases • Intramolecular lyases • Intramolecular lyases
37. 
1j31A
 255 215.7 3.?.?.? 10.51 3.?.?.? [Er] Hydrolases
38. 
1ydwA
 337 236.9 1. 1. 99. n 10.49 1. 1. 99. n [Er] Oxidoreductases • Acting on the CH-OH group of donors • With other acceptors
39. 
1ks2A
 212 212.0 5. 3. 1. n 10.35 5. 3. 1. n [Er] Isomerases • Intramolecular oxidoreductases • Interconverting aldoses and ketoses
40. 
1npdA
 276 273.0 1. 1. 1. n 10.33 1. 1. 1. n [Er] Oxidoreductases • Acting on the CH-OH group of donors • With NAD+ or NADP+ as acceptor
41. 
1to3A
 280 280.0 4. 1.?.? 10.32 4. 1.?.? [Er] Lyases • Carbon-carbon lyases
42. 
1ep0A
 183 183.0 5. 1. 3. n 10.25 5. 1. 3. n [Er] Isomerases • Racemases and epimerases • Acting on carbohydrates and derivatives
43. 
1f89A
 271 208.5 3.?.?.? 10.11 3.?.?.? [Er] Hydrolases
44. 
2qgyA
 376 275.2 5. 1. 2. n 10.08 5. 1. 2. n [Er] Isomerases • Racemases and epimerases • Acting on hydroxy acids and derivatives
45. 
2fbmA
 251 224.1 5. 3. 3. n 10.08 5. 3. 3. n [Er] Isomerases • Intramolecular oxidoreductases • Transposing C=C bonds
46. 
2decA
 325 238.6 2. 6. 1. n 10.01 2. 6. 1. n [Er] Transferases • Transferring nitrogenous groups • Transaminases
47. 
2e5fA
 325 238.6 2. 6. 1. n 9.96 2. 6. 1. n [Er] Transferases • Transferring nitrogenous groups • Transaminases
48. 
2gtrB
 258 219.3 5. 3. 3. n 9.93 5. 3. 3. n [Er] Isomerases • Intramolecular oxidoreductases • Transposing C=C bonds
49. 
2df8A
 325 237.8 2. 6. 1. n 9.91 2. 6. 1. n [Er] Transferases • Transferring nitrogenous groups • Transaminases
50. 
1oj7A
 390 234.7 1. 1. 1.? 9.89 1. 1. 1.? [Er] Oxidoreductases • Acting on the CH-OH group of donors • With NAD+ or NADP+ as acceptor
51. 
2ghsA
 289 201.5 3. 1. 8. n 9.81 3. 1. 8. n [Er] Hydrolases • Acting on ester bonds • Phosphoric triester hydrolases
52. 
1pbtA
 217 217.0 3. 1. 1. n 9.76 3. 1. 1. n [Er] Hydrolases • Acting on ester bonds • Carboxylic ester hydrolases
53. 
1ysjA
 351 188.2 3. 4. 11.? 9.71 3. 4. 17. n [Er] Hydrolases • Acting on peptide bonds (peptidases)
54. 
1npyA
 269 242.1 1. 1. 1. n 9.69 1. 1. 1. n [Er] Oxidoreductases • Acting on the CH-OH group of donors • With NAD+ or NADP+ as acceptor
55. 
2p4oA
 299 196.9 2. 7. 1. n 9.58 2. 7. 1. n [Er] Transferases • Transferring phosphorus-containing groups • Phosphotransferases with an alcohol group as acceptor
56. 
2qddB
 368 271.3 5. 5. 1.? 9.55 5. 5. 1.? [Er] Isomerases • Intramolecular lyases • Intramolecular lyases
57. 
1nzjA
 273 196.4 6. 1. 1. n 9.52 6. 1. 1. n [Er] Ligases • Forming carbon-oxygen bonds • Ligases forming aminoacyl-tRNA and related compounds
58. 
2f9cB
 319 174.7 2. 7. 7.? 9.52 2. 3. 1. n [Er] Transferases
59. 
1vp2A
 189 168.8 3. 6. 1. n 9.46 3.?.?.? [Er] Hydrolases
60. 
2qddA
 368 268.2 5. 5. 1.? 9.43 5. 5. 1.? [Er] Isomerases • Intramolecular lyases • Intramolecular lyases
61. 
2nqlA
 388 262.9 5.?.?.? 9.42 5. 1. 2. n [Er] Isomerases
62. 
2ps2A
 361 267.4 5. 5. 1.? 9.40 5. 5. 1.? [Er] Isomerases • Intramolecular lyases • Intramolecular lyases
63. 
2f9cA
 320 173.6 2. 7. 7.? 9.35 2. 3. 1. n [Er] Transferases
64. 
2hdyA
 403 261.1 4. 4. 1.? 9.28 4. 4. 1.? [Er] Lyases • Carbon-sulfur lyases • Carbon-sulfur lyases
65. 
2fu0A
 155 148.7 5. 2. 1. n 9.24 5. 2. 1. n [Er] Isomerases • cis-trans-Isomerases • cis-trans-Isomerases
66. 
1kxjA
 203 203.0 2. 4. 2.? 9.15 2. 4. 2.? [Er] Transferases • Glycosyltransferases • Pentosyltransferases
67. 
1vp4A
 412 259.2 2. 6. 1.? 9.10 2. 6. 1.? [Er] Transferases • Transferring nitrogenous groups • Transaminases
68. 
2cw5C
 236 170.4 2. 5. 1. n 9.07 2. 5. 1. n [Er] Transferases • Transferring alkyl or aryl groups, other than methyl groups • Transferring alkyl or aryl groups, other than methyl groups
69. 
2cw5A
 233 172.7 2. 5. 1. n 9.06 2. 5. 1. n [Er] Transferases • Transferring alkyl or aryl groups, other than methyl groups • Transferring alkyl or aryl groups, other than methyl groups
70. 
1qy9A
 290 139.9 5. 1. 1. n 9.03 5. 1. 1. n [Er] Isomerases • Racemases and epimerases • Acting on amino acids and derivatives
71. 
1vl0A
 277 260.9 1. 1. 1. n 8.92 1. 1. 1. n [Er] Oxidoreductases • Acting on the CH-OH group of donors • With NAD+ or NADP+ as acceptor
72. 
2hjsA
 332 229.1 1. 2. 1. n 8.92 1. 2. 1. n [Er] Oxidoreductases • Acting on the aldehyde or oxo group of donors • With NAD+ or NADP+ as acceptor
73. 
2fkbA
 157 138.7 5. 3. 3. n 8.85 5. 3. 3. n [Er] Isomerases • Intramolecular oxidoreductases • Transposing C=C bonds
74. 
1vgyA
 370 172.4 3.?.?.? 8.84 3. 4. 17. n [Er] Hydrolases
75. 
1sr0A
 361 282.5 3. 2. 1. n 8.77 3. 2. 1. n [Er] Hydrolases • Glycosidases • Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds
76. 
2b2pA
 361 280.6 3. 2. 1. n 8.77 3. 2. 1. n [Er] Hydrolases • Glycosidases • Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds
77. 
2b41A
 361 280.0 3. 2. 1. n 8.77 3. 2. 1. n [Er] Hydrolases • Glycosidases • Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds
78. 
2b2zA
 361 279.7 3. 2. 1. n 8.77 3. 2. 1. n [Er] Hydrolases • Glycosidases • Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds
79. 
2cw5B
 222 167.2 2. 5. 1. n 8.69 2. 5. 1. n [Er] Transferases • Transferring alkyl or aryl groups, other than methyl groups • Transferring alkyl or aryl groups, other than methyl groups
80. 
1ysjB
 348 178.1 3. 4. 11.? 8.62 3. 4. 17. n [Er] Hydrolases • Acting on peptide bonds (peptidases)
81. 
1ykwA
 414 273.2 4. 1. 1. n 8.61 4. 1. 1. n [Er] Lyases • Carbon-carbon lyases • Carboxy-lyases
82. 
2i51A
 191 151.8 1. 4. 3. n 8.56 1. 4. 3. n [Er] Oxidoreductases • Acting on the CH-NH2 group of donors • With oxygen as acceptor
83. 
2gwnA
 443 263.4 3. 5. 2. n 8.45 3. 5. 2. n [Er] Hydrolases • Acting on carbon-nitrogen bonds, other than peptide bonds • In cyclic amides
84. 
2pozB
 368 247.7 5.?.?.? 8.45 5.?.?.? [Er] Isomerases
85. 
2pozC
 367 249.0 5.?.?.? 8.41 5.?.?.? [Er] Isomerases
86. 
1yw1A
 389 228.2 1.?.?.? 8.37 1.?.?.? [Er] Oxidoreductases
87. 
2i51B
 188 148.8 1. 4. 3. n 8.36 1. 4. 3. n [Er] Oxidoreductases • Acting on the CH-NH2 group of donors • With oxygen as acceptor
88. 
2hszA
 222 192.1 3. 11. 1. n 8.31 3. 11. 1. n [Er] Hydrolases • Acting on carbon-phosphorus bonds • Acting on carbon-phosphorus bonds
89. 
2pozA
 373 243.9 5.?.?.? 8.28 5.?.?.? [Er] Isomerases
90. 
2o56G
 391 238.2 5.?.?.? 8.28 5.?.?.? [Er] Isomerases
91. 
2o56H
 389 237.2 5.?.?.? 8.28 5.?.?.? [Er] Isomerases
92. 
2podB
 372 236.2 5.?.?.? 8.28 5.?.?.? [Er] Isomerases
93. 
1ktnA
 250 249.0 4. 1. 2. n 8.27 4. 1. 2. n [Er] Lyases • Carbon-carbon lyases • Aldehyde-lyases
94. 
2o56A
 392 237.4 5.?.?.? 8.26 5.?.?.? [Er] Isomerases
95. 
2podA
 371 235.2 5.?.?.? 8.24 5.?.?.? [Er] Isomerases
96. 
2gl5A
 401 246.9 5.?.?.? 8.22 5.?.?.? [Er] Isomerases
97. 
1telB
 428 272.8 4. 1. 1. n 8.18 4. 1. 1. n [Er] Lyases • Carbon-carbon lyases • Carboxy-lyases
98. 
1nc5A
 363 195.0 3. 2. 1.? 8.15 5. 1. 3. n [Er] Unannotated function
99. 
2gdqA
 373 256.9 5.?.?.? 8.11 5.?.?.? [Er] Isomerases
100. 
1vk2A
 187 174.1 3. 2. 2.? 8.08 3. 2. 2.? [Er] Hydrolases • Glycosidases • Hydrolysing N-glycosyl compounds

Legend  1. PDB code: LINK to the Protein Data Bank

2. Protein Length: Length of the target protein

3. 3D-Hit Score: LINK to Structural Alignments
    black:  significant [>89]
    gray:   insignificant [<=89]

4. 3D-Hit EC Number: 4 LINKS to the Enzyme Structures Database
    blue:   significant and consistent
    gray:   insignificant or inconsistent

5. 3D-Fun Z-score: LINK to Structural Clusters (Groups)
    black:  significant [>3.1]
    gray:   insignificant [<=3.1]

6. 3D-Fun EC Number: 4 LINKS to the Enzyme Structures Database
    blue:   significant and consistent
    gray:   insignificant or inconsistent

7. Report Error: LINK to the Error Report Form
    Please, use this link and send us information
    about all incorrect assignments you found

8. Predicted Enzyme Function: the name of predicted function
    (LINKS to Enzyme Structures Database)
    black:  significant and consistent
    gray:   insignificant or inconsistent

    (click any column name to change sort order)


Please, cite the PDB-UF Database:

von Grotthuss M, Plewczynski D, Ginalski K, Rychlewski L, Shakhnovich EI
PDB-UF: database of predicted enzymatic functions for unannotated protein structures from structural genomics
BMC Bioinformatics. 2006 Feb 6;7(1):53 [pdf]


If you have any questions, please contact
Marcin von Grotthuss [mvg.at.paradox.harvard.edu]
Eugene Shakhnovich [eugene.at.belok.harvard.edu]